What step should be taken first when handling a potential rabies exposure?

When handling a potential rabies exposure, the first step should be to consult with the local health department. This action is crucial because public health officials are equipped to provide guidance on the necessary protocols and procedures for managing potential rabies exposures. They can assess the situation thoroughly considering local laws and regulations, advise on the vaccination status of any affected animals, and recommend the appropriate steps for human exposure.

The local health department also serves as a central resource to coordinate public health responses to rabies cases, ensuring that appropriate measures are taken to protect both the exposed individual and the community. They can also provide directions on reporting the incident according to state laws, which is essential for tracking rabies exposure incidents.

The other options, while important, follow this initial consultation. Understanding the animal's vaccination record, evaluating its behavior, and isolating it from other pets are steps that are considered in conjunction with the guidance from the health department rather than being primary initial responses.